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This study sought to investigate the association of the pre-procedural N/L ratio within-hospital and long-term outcomes among STEMI patients undergoing primary percutaneous coronary intervention (PCI).
A total of 682 STEMI patients who were admitted within the first six hours ofsymptom onset were enrolled andstratified according to tertiles of N/L ratio based upon blood samples obtained in the emergency room upon admission.
The mean follow-up period was 43.3 months (1–131 months). In-hospital in-stent thrombosis, non-fatal myocardial infarction, and cardiovascular mortality increased as the N/L tertile ratio increased (p<0.001, p<0.001, p=0.003, respectively). Long-term in-stent thrombosis, non-fatal myocardial infarction and cardiovascular mortality also increased as the N/L ratio increased (p<0.001, p<0.001, p=0.002, respectively). Onmultivariate analysis, N/L ratio was an independent predictor of in-hospital major advanced cardiac events (MACE) (OR 1.189, 95% CI 1.000–1.339; p<0.001) and an independent predictor of long-term MACE (OR 1.228, 95% CI 1.136–1.328; p<0.001).
N/L ratio was an independent predictor of both in-hospital and long-term adverse outcomes amongSTEMI patients undergoing primary PCI. Our results suggest that the pre-procedural N/L ratio is an inexpensive and universally available parameter that can be used for STEMI risk stratification.
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Acute Coronary Syndromes: Basic IV
Abstract Category: 2. Acute Coronary Syndromes: Basic
Presentation Number: 1256-180
- 2013 American College of Cardiology Foundation