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In this study, we assessed efficacy of CTO–PCI among patients divided by severity of syntax score to establish role of PCI among patients with CTO.
We investigated consecutive 245 patients who underwent CTO–PCI adjunctive to medical therapy. All those patients were assessed by syntax score based on their initial angiogram. We compared them according to results of CTO–PCI, and investigated their long–term outcomes among three groups divided by SYNTAX score severity (low score (<20), medium score (20–32), and high score (>32). Primary end point of this study was major adverse cardiac event (MACE) comprise to all cause death, non–fatal myocardial infarction, additional revascularization including bypass surgery during subsequent follow up periods.
Mean age(y) is 64.8±11, 68.2±10, and 69.4±11 (P=0.02), ejection fraction (%) was 57.6±15, 55.9±15, and 50.7±15 (P=0.01). According to syntax score assessment, specific score at CTO site is 10.2±3, 15.2±7, and 15.4±7 (P<0.001). Procedural success rate of CTO–PCI among those groups are 86.0%, 89.7%, and 78.7 % respectively (P=0.15). According to cumulative MACE analysis, in contrast to low syntax score group, success of CTO–PCI is effective compared to failure of CTO–PCI group among patients with high and intermediate syntax score.
Success of CTO–PCI may improve long–term benefits among high syntax subsets, but role of PCI among low syntax subset needs further investigation.
Poster Sessions, Expo North
Saturday, March 09, 2013, 3:45 p.m.–4:30 p.m.
Session Title: Chronic Total Occlusions
Abstract Category: 44. TCT@ACC–i2: Coronary Intervention, CTO
Presentation Number: 2103–234
- 2013 American College of Cardiology Foundation