Author + information
- Shirda Imami,
- Matthijs Bax,
- Arnout Haasdijk,
- Carl Schotborgh,
- Jan Willem Bech,
- Lucas Savalle and
- Pranobe Oemrawsingh
Multi–vessel disease (MVD) and gender are factors known to affect prognosis in ST–elevation myocardial infarct (STEMI). This study evaluates long–term outcome in women with MVD and STEMI after primary PCI (PPCI).
Consecutive patients with STEMI and MVD (n=1119), presenting for PPCI between January 2006 and January 2010, without shock or previous CABG (n= 832), were included. Patients were followed for 3.5 ± 1.5 yrs.
Baseline and procedural characteristics are shown in Table 1. DES were significantly more often used in women (40% vs. 33%, p=0.04) at PPCI. Treatment for non–Culprit lesions (nCL) was more often invasive (PCI or CABG) in men (M 78% vs. F 22%; p=0.04) Discharge medication was equivalent in both sexes. Kaplan–Meier analysis showed worse survival for women at 1 year (p=0.009) and at long term FU (p=0.004). Unadjusted 1 year (HR 2.30; 95% CI 1.21–4.35, p=0.01) and long–term mortality (HR 1.97; 95% CI 1.23–3.15, p=0.005) was significantly higher in women. Multivariate analysis however, reveals age (HR 1.06; 95% CI 1.04–1.09, p<0.001), previous MI (HR 1.94; 95% CI 1.95; 95% CI 1.05–3.61, p=0.04) and hypertension (HR 1.53; 95% CI 0.96–2.44, p=0.08) but not gender (HR 1.03; 95% CI 0.62–1.69, p=0.92) as independent predictors of mortality at long–term FU.
Not gender, but age, hypertension and previous AMI are predictors of long–term survival in STEMI patients with MVD.
Poster Sessions, Expo North
Saturday, March 09, 2013, 3:45 p.m.–4:30 p.m.
Session Title: Multivessel Disease
Abstract Category: 45. TCT@ACC–i2: Coronary Intervention, Multivessel disease
Presentation Number: 2104–256
- 2013 American College of Cardiology Foundation