Author + information
- Karolina Szummer,
- Evans Marie,
- Juan Jesus Carrero,
- Robert Edfors,
- Jonas Spaak,
- Stefan Jacobson and
- Tomas Jernberg
Survival after myocardial infarction (MI) has improved markedly during the last decade. It is still unknown whether this improvement in survival also confers to MI patients with renal impairment.
We used the SWEDEHEART registry covering all emergency hospitals in Sweden. All MI cases with available creatinine on admission who were admitted to a coronary care unit between 2003 and 2010 were used in the analyses (n=147955). Glomerular filtration rate (GFR) was estimated using the abbreviated MDRD formula, and patients were categorized according to GFR into 4 groups (<30; 30–59; 60–89, >90 ml/min/1.73m2). The primary outcome was in-hospital and 1-year survival, which had complete follow-up.
From 2003 to 2010 the variables predicting GFR used in the MDRD formula changed: the proportion of males increased from 62.7 to 64.7%, creatinine decreased from 96 (80–119) to 86 (72–106) µmol/l [median (interquartile range)], and age on admission decreased from 74 (64–81) to 72 (63–81). Overall, in-hospital mortality decreased from 7.3 to 4.8% and 1-year mortality from 21.0 to 15.5%. The one-year mortality in each renal function category improved (figure).
In-hospital and 1-year survival following a myocardial infarction in patients with renal impairment has improved although it remains high.
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Comorbidity and ACS: COPD, Renal Dysfunction, Diabetes
Abstract Category: 1. Acute Coronary Syndromes: Clinical
Presentation Number: 1257-190
- 2013 American College of Cardiology Foundation