Author + information
- Kunihiro Shimamura,
- Takashi Akasaka,
- Yasushi Ino,
- Yoshihisa Nakagawa,
- Keiichi Igarashi,
- Kengo Tanabe,
- Yoshihiro Morino,
- Masashi Iwabuchi,
- Kazuo Kimura,
- Ken Kozuma and
- Takeshi Kimura
The long term outcome of in complete stent apposition (ISA) after stent implantation remains unclear. The aim of this study was to evaluate serial changes of ISA after everolims–eluting stent implantation by using optical coherence tomography (OCT).
Randomized Evaluation of Sirolims–eluting versus Everolims–eluting stent Trial (RESET) was a prospective dual–arm randomized trial of everolims–eluting stents (EES) and sirolims–eluting stents (SES) in 3197 patients with coronary artery disease. From the RESET trial, 44 patients with everolims–eluting stents who underwent serial OCT examination (post–stenting and 12–month follow–up) were investigated.
At post–stenting, ISA was observed in 38 (86%) EES. Mean malapposed distance (distance from stent strut to lumen surface) was 366 ± 225 µm at post–stenting. At 12–month follow–up, 27 (76%) ISA was resolved, however 9 (24%) was persistent. The mean malapposed distance was 165 ± 276 µm at 12–month follow–up. Receiver–operating curve analysis identified a malapposed distance > 410µm, (area under the curve, 0.95) as separating persistent from resolved ISA.
The stent with malapposed distance > 410µm at post–stenting has a high risk for persistent stent malapposition at 12–month follow–up in EES. OCT can predict persistent stent malapposition and provide useful information to optimize percutaneous coronary intervention.
Poster Sessions, Expo North
Sunday, March 10, 2013, 9:45 a.m.–10:30 a.m.
Session Title: Intravascular Imaging: IVUS and OCT
Abstract Category: 38. TCT@ACC–i2: Intravascular Imaging and Physiology
Presentation Number: 2108–236
- 2013 American College of Cardiology Foundation