Author + information
- Masayuki Taniike,
- Masami Nishino,
- Naoki Mori,
- Yasuharu Lee,
- Takahiro Yoshimura,
- Daisuke Nakamura,
- Nobuhiko Makino,
- Hiroyasu Kato,
- yasuyuki egami,
- Ryu Shutta,
- Hisaki Morita,
- Jun Tanouchi and
- Yoshio Yamada
Cutting balloon angioplasty (CBA) is one of proposed treatments for in–stent restenosis (ISR) but re–restenosis rate after CBA is relatively high. In this study, we investigated whether optical coherence tomography (OCT) detected tissue characteristics can affect re–restenosis after CBA for ISR.
Fifty–six consecutive patients with ISR who received OCT–guided CBA were enrolled. We divided our patients into TLR group in whom we performed target lesion revascuralization (TLR) for re–restenosis over 3 months after CBA for ISR and non–TLR group in whom we didn't perform TLR. We compared the incidence of drug–eluting stent, phase of ISR, ISR pattern, the OCT parameters of ISR before CBA including restenotic tissue structure/backscatter, microvessels, minimum lumen area, balloon size and maximal inflation pressure between the two groups.
The rate of TLR was 21.4%. The incidence of microvessels and heterogeneous or layered pattern in TLR group (n=12) was significantly higher than non–TLR group (n=44) while the other parameters showed non–significant differences (table).
We frequently avoided TLR by CBA for ISR (approximately 80%). The incidence of microvessels and heterogeneous or layered pattern in ISR detected by OCT may affect re–restenosis after CBA for ISR.
|TLR group (n=12)||non-TLR group (n=44)||p value|
|age (years old)||70.7±2.0||71.6±1.5||0.73|
|Bare metal stent/Drug eluting stent, n (%)||4/8 (33.3/66.7)||16/28 (36.4/63.6)||0.84|
|Phase of ISR, Early(<1yr)/Late(>=1yr), n (%)||8/4 (66.7/33.3)||28/16 (63.6/36.4)||0.85|
|ISR Pattern, Focal/Diffuse, n (%)||5/7 (41.7/58.3)||21/23 (47.8/52.3)||0.71|
|Restenotic tissue structure, Homogeneous/Heterogeneous/Layered, n (%)||0/8/4 (0/66.7/33.3)||34/1/9 (77.3/2.3/20.4)||<0.01|
|Restenotic tissue backscatter, High/Low, n (%)||2/10 (16.7/83.3)||3/41 (6.8/93.2)||0.29|
|Microvessels, n (%)||12 (100)||16 (36.4)||<0.01|
|Minimum lumen area (mm2)||1.26±0.16||1.35±0.17||0.54|
|CBA balloon size (mm)||2.86±0.09||2.97±0.04||0.26|
|Maximal inflation pressure of cutting balloon (atm)||9.00±0.76||8.12±0.36||0.26|
Poster Sessions, Expo North
Sunday, March 10, 2013, 9:45 a.m.–10:30 a.m.
Session Title: Intravascular Imaging: IVUS and OCT
Abstract Category: 47. TCT@ACC–i2: Coronary Intervention, Devices
Presentation Number: 2108–262
- 2013 American College of Cardiology Foundation