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Skin Perfusion Pressure (SPP) has been proposed as a method to predict wound heal of critical limb ischemia (CLI). However association between SPP level after endovascular therapy (EVT) and wound heal of CLI remain unclear. The aim of this study was to determine the predictive value of SPP for wound heal after EVT.
EVT was performed for consecutive 113 patients with CLI (123 limbs) in this study. SPP was measured within 48hours after EVT and status of wound heal were recorded. Patients who had uncontrolled sepsis or died within 1 month after procedure were excluded.
Technical success rate was 94.3% (n=116), and wound heal rate was 78.9% (n=97). SPP value after EVT of patients with wound heal was significantly higher than without wound heal (44.2±15.6mmHg vs. 27.5±10.4mmHg, P<0.001). ROC analysis of SPP after EVT to predict wound heal had an area under the curve of 0.81 (95%CI: 0.723–0.899, P<0.001). The optimal cut off point for predicting wound heal was 30mmHg with a sensitivity of 81.4%, a specificity of 69.2%. Patients whose SPP value after EVT were more than 30mmHg had a wound heal rate of 90.8%, compared with 50% in those less than 30mmHg. Binary logistic regression analysis demonstrated that SPP after EVT was an independent predictor for wound heal in patients with CLI (P<0.001).
SPP after EVT is an independent predictor for wound heal in patients with CLI. In our study, SPP value of 30mmHg as the best threshold value to predict wound heal after EVT.
Moderated Poster Contributions
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.–4:30 p.m.
Session Title: Endovascular Intervention
Abstract Category: 41. TCT@ACC–i2: Carotid, Neurovascular, and Endovascular Intervention
Presentation Number: 2109M–217
- 2013 American College of Cardiology Foundation