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The long pentraxin 3 (PTX3) is a member of the pentraxin family believed to reflect vascular inflammation. The aim of this analysis was to assess the long-term prognostic value of PTX3 in a population of patients admitted with severe myocardial infarction (MI).
Blood samples were drawn 4–6 days following admission in 282 patients. PTX3 was assessed in citrated plasma by ELISA methodology. The patients were divided into quartiles based on their PTX3 plasma concentration.
After a follow-up of 45 months, 81 of 282 patients (28.7%) had either died or suffered from a new myocardial infarction. However, there was no significant difference in risk of a new event between the PTX3 quartiles (data displayed in the table).
PTX3 levels 4–6 days following admission failed to provide prognostic information in patients admitted with an MI.
|PTX 3 (ng/mL) quartile||Event during 45 months follow-up, n (%)||OR (95% CI)|
|Q4 (>5.6)||18 (33.3)||1.02 (0.48–2.19)|
|Q3 (4.10–5.59)||27 (39.1)||1.97 (0.95–4.08)|
|Q2 (2.77–4.09)||19 (26.4)||1.10 (0.51–2.34)|
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Acute Coronary Syndromes: Role of Inflammation
Abstract Category: 1. Acute Coronary Syndromes: Clinical
Presentation Number: 1258-202
- 2013 American College of Cardiology Foundation