Author + information
- Hiromasa Otake,
- Toshiro Shinke,
- Masayuki Nakagawa,
- Hirotoshi Hariki,
- Takumi Inoue,
- Yu Taniguchi,
- Ryo Nishio,
- Tsuyoshi Ohsue and
- Ken–ichi Hirata
Delayed arterial healing and late restenosis are a matter of concern of drug–eluting stents. We sought to investigate natural course of arterial healing after everolimus–eluting stents (EES) implantation by OCT.
We enrolled a total of 220 lesions in 161 patients treated with EES and performed follow–up OCT at various timing regardless of symptoms. All the lesions were classified according to the timing of follow–up OCT and were compared OCT findings among the groups. In additionto the standard OCT variables, a neointimal unevenness score (NUS) was calculated for each cross–section as maximum NIT in the cross–section divided by the average NIT of the same cross–section. Then, average NUS were calculated for each stent to quantitatively evaluate unevenness of neointimal distribution within the stent.
Average NIT, average neointima area, and %neointima obstructionprogressively increased within the first 12 months, and reached a plateau at the level of 120µm for NIT, 1.0mm2for neointima area, and 16.0% for %neointima obstruction 12 months after stenting. Also, %uncovered and malapposed struts decreased along with follow–up durations with a very few incidences of those findings at 12 months. NUS reached the highest level at 3 months and then reached a plateau at 9 months after stenting.
Neointimal progression within EES appears to slow–down 1 year after stenting with a very few incidences of uncovered and malapposed struts.
West, Room 2004
Monday, March 11, 2013, 8:45 a.m.–8:55 a.m.
Session Title: Intravascular Imaging: Focus on OCT
Abstract Category: 38. TCT@ACC–i2: Intravascular Imaging and Physiology
Presentation Number: 2912–7
- 2013 American College of Cardiology Foundation