Author + information
- Mane Arabyan,
- Wen–Loong Yeow,
- Takashi Matsumoto,
- Asma Hussaini,
- Takahiro Shiota,
- Swaminatha Gurudevan,
- Vinny Ram,
- Rehan Kanji,
- Alfredo Trento and
- Saibal Kar
There is a paucity of data of patients with severe functional mitral regurgitation (FMR) not treated with surgery. There is no data supporting surgery affects outcome in FMR. The MitraClip is a less invasive procedure, which may improve survival.
As off September 2012, all consecutive FMR patients on the MitraClip waitlist were assessed and their survival (from time of consent) was compared to consecutive FMR patients that underwent the MitraClip procedure (from time of procedure) in our center.
There were 52 patients on the waitlist and 99 patients that underwent the MitraClip procedure. Baseline characteristics were similar for age (74±10 years vs 75±11years, p=0.42), male (28 (54%) vs 61 (62%), p=0.36), Society of Thoracic Surgeons mortality score (10±10% vs 11±8%, p=0.64), New York Heart Association functional class ≥ III (40 (93%) vs 92 (93%), p=0.98), and MR grade ≥ 3+ (43 (100%) vs 98 (100%)). Post procedure MR ≤ 2+ was 93%. At a median follow up of 12 months, Kaplan–Meier estimate of actuarial survival was 75.1% for waitlist patients (vs 88.2% following the MitraClip procedure, p=0.026).
Patients with significant functional MR have high mortality. The MitraClip procedure may reduce mortality in these patients.
Poster Sessions, Expo North
Saturday, March 09, 2013, 10:00 a.m.–10:45 a.m.
Session Title: Evolving Concepts for the Optimal Management of Mitral Regurgitation from E–Clip to Robotics
Abstract Category: 32. Valvular Heart Disease: Therapy
Presentation Number: 1111–77
- 2013 American College of Cardiology Foundation