Author + information
- Anand Deshmukh,
- Jitendra Pandya,
- Daniel Hilleman,
- Michael White,
- Thomas Lanspa,
- Michael DelCore,
- Claire Hunter,
- Aryan Mooss and
- Dennis Esterbrooks
There is conflicting data on impact of obesity on long- term cardiovascular outcomes in patients presenting with acute ST elevation myocardial infarction.
We conducted a retrospective analysis of all patients undergoing percutaneous coronary intervention (PCI) at our center from January 2003 through May 2010. We collected demographic, clinical and procedural characteristics on these patients. The patients were divided into two groups based on their Body Mass Index (BMI); group 1 consisted of non- obese patients with BMI < 30 and group 2 consisted of obese patients with BMI ≥ 30. The primary endpoint was major adverse cardiac events (MACE), which was a composite of annual incidence of hard clinical endpoints including all cause mortality, recurrent acute coronary syndrome (RACS) and cerebrovascular accident (CVA)/ transient ischemic attack (TIA). Secondary endpoints were annual incidence all cause mortality, RACS, CVA/ TIA, repeat revascularization and in-hospital major bleeding.
A total of 410 patients qualified for the study (259 non-obese and 151 obese patients). The incidence of traditional risk factors such as hypertension and diabetes mellitus was more common in obese patients, smoking was more common in the non-obese patients, however left ventricular ejection fraction was similar in both the groups. The primary endpoint occurred in 17% of non-obese patients and 14.6 % in obese patients (p=0.58). Among the secondary endpoints, the annual incidence of all cause mortality was 3.5 % in group 1 and 2.6% in group 2 (p= 0.77); CVA/TIA was 1.2 % in group 1 and 0.7 % in group 2 (p= 1.0), RACS was 13.1 % in group 1 and 13.9 % in the group 2 (p = 0.88), repeat revascularization was 12.4 % in group 1 and 13.2 % in group 2 (0.88) and in-hospital major bleeding was 2.3 % in group 1 and 1.3 % in group 2
There is no difference in MACE or all cause mortality between obese and non- obese patients presenting with STEMI at one year.
Poster Sessions, Expo North
Monday, March 11, 2013, 9:45 a.m.-10:30 a.m.
Session Title: Acute Coronary Syndromes: Clinical Outcomes
Abstract Category: 1. Acute Coronary Syndromes: Clinical
Presentation Number: 1299-180
- 2013 American College of Cardiology Foundation