Author + information
- Ravi Ranjan,
- Eugene Kholmovski,
- Joshua Blauer,
- Sathya Vijayakumar,
- Nelly Volland,
- Gregory Gardner,
- Dennis L. Parker,
- Rob MacLeod and
- Nassir Marrouche
In current fluoroscopy based electrophysiology (EP) systems when ablating we do not get a direct feedback of ablation related tissue changes. Here we describe a 3 Tesla MRI Electrophysiology system providing direct feedback of acute tissue changes from ablation.
Studies were carried out in pigs (n=39). A 3T MRI scanner was used for the study. MRI compatible EP catheters with active tracking coils and irrigated tip were used. Endocardial shells of all the cardiac chambers were created from magnetic resonance angiograms and were imported in the real time visualization software, showing the cardiac structure along with the catheter.
Successful right atrial ablation was carried out in all 39 animals, left atrial ablation in 7 animals, electro-anatomical mapping in 16 animals and ventricular ablation in 16 animals. We were able to record ECG and intra-cardiac signals during active imaging and pacing. Electrophysiology study was carried out recording 35 +/-19 point coordinates and local electrograms per study. Ablation lesions were acutely visualized using late gadolinium enhancement and confirmed using gross pathology.
A 3T MRI based complete EP system has been developed. It has all the capabilities of currently used fluoroscopy based EP system and provides the significant advantage of being able to see ablation related acute tissue change, and also visualize cardiac structures without any exposure to ionizing radiation for the subject or the operator.
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Arrhythmias: AF/SVT VII
Abstract Category: 4. Arrhythmias: AF/SVT
Presentation Number: 1236-34
- 2013 American College of Cardiology Foundation