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There is a paucity of data to estimate the number of people living with congenital heart disease (CHD) in the general population. The most recent estimates were for the years 2000-2005 when increasing CHD prevalence was documented in adults and children. Our goal was to provide current estimates of life-time CHD prevalence.
Using a unique identifier assigned at birth, the Quebec CHD database contains 28 years of longitudinal data on all those born with CHD from 1983-2010. The database was created by fusing claims-data from inpatient, outpatient and death registry sources. Published algorithms to identify CHD diagnoses (ICD 9-10) were applied. Severe CHD was defined as tetralogy of Fallot, truncus arteriosus, transposition complexes, endocardial cushion defects, and univentricular hearts. All remaining lesions were classified as other CHD. We used a latent class Bayesian model that combines case definitions from multiple data sources including physician billing, hospitalization and surgical data to obtain point and interval estimates of CHD prevalence.
We identified 108,726 CHD patients from 1983 to 2010. We estimated the prevalence of CHD detected in the first year of life at 8.16 per 1000 live-births (95% CI 7.90, 8.43) from 1998-2005. In 2010, the prevalence estimates in children and adults (95% CI) were 11.85 /1000 (11.43, 12.30) among children and 6.07 /1000 (5.97, 6.17) among adults. The prevalence estimates of severe lesions were 1.76 /1000 (1.68, 1.84) among children and 0.64 /1000 (0.61, 0.67) among adults.
We report data on life-time prevalence of CHD in the general population. Birth prevalence rates are comparable to those published by the Centers for Disease Control in the United States. In 2010, the prevalence of CHD in adults was 6.07 per 1000 corresponding to a 50% increase compared to the year 2000. These results should help inform the generation of contemporary estimates of the number of people living with CHD in the United States and other industrialized nations.
Oral Contributions West, Room 3005
Sunday, March 10, 2013, 11:00 a.m.-11:15 a.m.
Session Title: Congenital Cardiology Solutions: Adult
Abstract Category: 12. Congenital Cardiology Solutions: Adult
Presentation Number: 924-4
- 2013 American College of Cardiology Foundation