Author + information
Outcome data regarding post-operative acute coronary syndrome treated with percutaneous coronary intervention (PCI) is limited.
We assessed outcomes of 517 patients who underwent PCI within 7 days following surgery across 44 hospitals from January 2010 to December 2011. Post-operative PCI patients were compared to all other PCI patients using propensity matched analysis. A recursive partitioning model identified characteristics associated with in-hospital mortality.
517 patients underwent PCI within 7 days following surgery compared with 64,658 patients who underwent PCI without surgery within 7 days. In unadjusted analysis, post-surgical PCI patients had higher in-hospital mortality (6.96% vs. 1.33%), CVA (0.96% vs.0.26%), bleeding events (6.96% vs. 2.6%), heart failure (6.96 vs. 2.36%), and cardiogenic shock (7.16% vs. 1.95%). After propensity matching, mortality remained higher in post-surgical patients (6.5% vs. 3.96%, OR: 1.7 [1.1–2.6], p=.02), with the effect concentrated in otherwise low risk patients (defined as <1% predicted mortality in a non-surgical setting) where recent surgery was strongly associated with death (OR: 8.4 [4.1–17.2], p<0.001).
PCI performed within 7 days following a surgical procedure is associated with an increased risk of early mortality. While some of this increased risk is related to an adverse clinical profile, higher mortality is also observed in patients otherwise considered low risk for PCI.
Poster Sessions, Expo North
Saturday, March 09, 2013, 3:45 p.m.-4:30 p.m.
Session Title: ACS Therapy: Key Observational Data
Abstract Category: 3. Acute Coronary Syndromes: Therapy
Presentation Number: 1168-180
- 2013 American College of Cardiology Foundation