Author + information
- Gavin Hickey,
- Omar Batal,
- Nadeem Kolia,
- Sandeep Patel,
- Bhavna Balaney,
- Zeina Dardari,
- Vivek Reddy,
- Tudor Jovin,
- Maxim Hammer,
- Mark Schmidhofer and
- Hunter Champion
Cardiomyopathy (CM) in patients admitted with acute ischemic stroke has not been investigated previously.
A prospective registry of 1,761 patients admitted with diagnosis of acute ischemic stroke from 2009-2010 was used to identify patients with systolic CM.
Echocardiography was performed on 1,594 (90%) of all patients. We identified 273 (15.5%) patients with systolic CM during admission for acute ischemic stroke. Patients with CM had a mean age of 69.5 ± 13.8, and 96 (35%) were female. Follow-up echocardiography was available on 90 patients. In total, 174 (10.9%) had newly diagnosed CM. Of these, 40 (23%) had dilated CM likely representing undiagnosed chronic CM. New CM was attributed to type 1 MI in 10 patients. The remaining patients with new, non-dilated CM were classified as being classic for stress induced CM (SICM), or atypical for SICM based on wall motion abnormalities, changes on electrocardiogram, TnI elevation, and recovery of systolic function. We identified 26 cases of classic SICM. In patients with systolic CM (new or previously known) in-hospital mortality was significantly higher than patients without CM (15% vs 4.4%, p<0.0001).
Patients with CM are at significantly higher risk for in-hospital death compared to those with normal systolic function. The rate of SICM in acute ischemic stroke approaches 10% of patients found to have systolic CM. Many cases of new CM with atypical features likely represent variants of classic SICM.
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Role of Comorbidities in Heart Failure: From Diabetes, Pulmonary Disease, Hypertension to Atrial Fibrillation
Abstract Category: 15. Heart Failure: Clinical
Presentation Number: 1263-275
- 2013 American College of Cardiology Foundation