Author + information
- Amber Marie Otten,
- Jan Paul Ottervanger,
- Anita Kloosterman,
- Arnoud Hof,
- Marcel Gosselink,
- Jan-Henk Dambrink,
- Jan Hoorntje,
- Harry Suryapranata and
- Angela Maas
Spontaneous coronary artery dissection (SCAD) is a relative rare cause of myocardial infarction and is probably more common in younger women. However, until now, predisposing risk factors, efficacy of primary PCI, clinical outcome and prognosis of SCAD in younger women are poorly assessed.
Between 1998 and 2010 all patients with ST elevation myocardial infarction (STEMI) admitted in our hospital are included in a prospective data base. We retrospectively analyzed all coronary angiograms of women <50 years.
During the study period a total of 8152 patients with STEMI were admitted, including 263 women < 50 years. In these women, SCAD was observed in 26 patients (10%). Baseline characteristics, including smoking, were comparable between women with and without SCAD. Angiographic data showed that the left anterior descending artery was more often the infarct related vessel in patients with SCAD(85% vs 55%, p=0.001). Women with SCAD were more often conservatively treated than those without SCAD(figure). TIMI 3 flow was comparable between both groups before angiography (30% vs 35%, p=0.62). After angiography, however, TIMI 3 flow was less common observed in patients with SCAD(68% vs 96%, p<0.001).
SCAD can be observed in 10% of women <50 years presenting with STEMI. Patients with SCAD have a lower TIMI flow after PCI and receive less often interventional treatment.
Poster Sessions, Expo North
Saturday, March 09, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Gender, Dissection, Outcomes from ACS
Abstract Category: 1. Acute Coronary Syndromes: Clinical
Presentation Number: 1170-189
- 2013 American College of Cardiology Foundation