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Co-morbidities frequently accompany heart failure (HF) and further impair quality of life and mortality, although the pathophysiology remains unclear. We assessed the prevalence and determinants of co-morbidities in patients with HF and its relation with venous congestion and prognosis.
A total of 3226 outpatients with chronic HFs were included in this analysis of the European Heart Failure pilot survey. Venous congestion was defined as presence or absence of raised jugular venous pressure (>6 cm) and peripheral edema. Clinical endpoints were all-cause mortality and HF hospitalization.
711 patients (23%) had at least one sign of congestion. There was a clear relation between signs of congestion and the presence of comorbidities. Patients with congestion more often had chronic kidney disease (51 vs 38 %, P >4 co-morbidities had a higher mortality (HR 2.43, P < 0.0001) and were more often re-hospitalized (HR 2.88, P < 0.0001).
Co-morbidities are prevalent in patients with chronic HF and are related to clinical signs of congestion. Co-morbidities, in particular diabetes, chronic kidney disease and anemia, were related to increased risks of mortality and HF hospitalizations.
Poster Sessions, Expo North
Sunday, March 10, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Role of Comorbidities in Heart Failure: From Diabetes, Pulmonary Disease, Hypertension to Atrial Fibrillation
Abstract Category: 15. Heart Failure: Clinical
Presentation Number: 1263-290
- 2013 American College of Cardiology Foundation