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3D echocardiography is widely used in perinatology, but quantitation of fetal cardiac imaging is not prevalent. This in vitro validation study was designed to assess the accuracy and precision of left ventricular (LV) volume and mass determinations of small hearts based on Four-dimensional volumes.
Five fresh rabbit hearts were pumped at stroke volumes (SV) ranging from 1 to 5 ml by a calibrated pulsatile pump. 4D volume data was recorded using a Philips® iU-22 with an X6-1 matrix probe at each SV. LV volume and mass were calculated using QLab™ GI-3DQ by manually tracing endocardial and epicardial boundaries of stacked contours from base to apex and compared to displacement values.
Linear regression for echo-derived SV and mass showed excellent correlation with displacement (SV: R2=0.83, p<0.001; mass: R2=0.91, p<0.001). Bland-Altman analyses showed bias consistent with a slight overestimation for SV (+0.302267) and mass (+1.424667), and 96% of points within a 95% Cl.
High resolution 4D imaging along with QLab™ GI-3DQ demonstrated both accuracy and precision in the quantification of LV chamber volumes and mass for small hearts.
Moderated Poster Contributions
Poster Sessions, Expo North
Saturday, March 09, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Imaging: 3D Echocardiography
Abstract Category: 18. Imaging: Echo
Presentation Number: 1180M-334
- 2013 American College of Cardiology Foundation