Author + information
- Amil Shah,
- Chung-Lieh Hung,
- Susan Cheng,
- Kunihiro Matsushita,
- Kenneth Butler,
- Suma Konety,
- Dalane Kitzman and
- Scott Solomon
Left ventricular (LV) torsion describes the opposing basal to apical myocardial systolic twisting and appears to increase with advancing age. Few data exist regarding normal reference values, particularly in healthy elderly.
Of 1,130 community dwelling elderly from the Atherosclerosis Risk in Communities (ARIC) study with analyzable three-dimensional (3D) echos and EF≥50%, we identified 124 without heart failure (HF) or HF risk factors (RFs), 961 with RFs but no HF, and 45 with HF and preserved EF (HFpEF). 3D LV torsion was measured using validated software (TomTec 4D LV-Analysis 3.0).
In the no HF, no RFs group, age was 73.4±4.9 (range 66–88 years), 85% were female, 94% were white, and LVEF was 67.6±4.7%. Mean torsion was 1.78±0.60 degrees (95% Cl: 0.58–2.98o). In this group, higher torsion was associated with older age, female gender, higher systolic BP, higher LVEF, smaller LV volumes, concentric remodeling, and worse diastolic indices. Torsion did not differ between persons without RFs vs. those with HF RFs (1.73±0.59, p=0.70) or vs. those with HF (1.67±0.58, p=0.38), even after adjusting for differences in age, gender, race, co-morbidities, and cardiac structure.
Using a well-characterized population-based study, we developed normative reference ranges for torsion among healthy elderly persons without HF RFs, and found that torsion did not differ significantly between these subjects compared to elderly with RFs but no HF, or those with established HFpEF.
Moderated Poster Contributions
Poster Sessions, Expo North
Saturday, March 09, 2013, 3:45 p.m.-4:30 p.m.
Session Title: Imaging: 3D Echocardiography
Abstract Category: 18. Imaging: Echo
Presentation Number: 1180M-338
- 2013 American College of Cardiology Foundation