Author + information
- Received February 13, 2012
- Revision received November 20, 2012
- Accepted November 22, 2012
- Published online March 19, 2013.
- Dhanunjaya Lakkireddy, MD⁎,⁎ (, )
- Donita Atkins, RN⁎,
- Jayasree Pillarisetti, MD⁎,
- Kay Ryschon, MS†,
- Sudharani Bommana, MPhil⁎,
- Jeanne Drisko, MD‡,
- Subbareddy Vanga, MBBS, MS§ and
- Buddhadeb Dawn, MD⁎
- ↵⁎Reprint requests and correspondence:
Dr. Dhanunjaya Lakkireddy, EP Research–KU Cardiovascular Research Institute, Bloch Heart Rhythm Center, Mid America Cardiology, University of Kansas Hospital and Medical Center, 3901 Rainbow Boulevard, Kansas City, Kansas 66160
Objectives The purpose of this study was to examine the impact of yoga on atrial fibrillation (AF) burden, quality of life (QoL), depression, and anxiety scores.
Background Yoga is known to have significant benefit on cardiovascular health. The effect of yoga in reducing AF burden is unknown.
Methods This single-center, pre-post study enrolled patients with symptomatic paroxysmal AF with an initial 3-month noninterventional observation period followed by twice-weekly 60-min yoga training for next 3 months. AF episodes during the control and study periods as well as SF-36, Zung self-rated anxiety, and Zung self-rated depression scores at baseline, before, and after the study phase were assessed.
Results Yoga training reduced symptomatic AF episodes (3.8 ± 3 vs. 2.1 ± 2.6, p < 0.001), symptomatic non-AF episodes (2.9 ± 3.4 vs. 1.4 ± 2.0; p < 0.001), asymptomatic AF episodes (0.12 ± 0.44 vs. 0.04 ± 0.20; p < 0.001), and depression and anxiety (p < 0.001), and improved the QoL parameters of physical functioning, general health, vitality, social functioning, and mental health domains on SF-36 (p = 0.017, p < 0.001, p < 0.001, p = 0.019, and p < 0.001, respectively). There was significant decrease in heart rate, and systolic and diastolic blood pressure before and after yoga (p < 0.001).
Conclusions In patients with paroxysmal AF, yoga improves symptoms, arrhythmia burden, heart rate, blood pressure, anxiety and depression scores, and several domains of QoL. (Yoga on Arrhythmia Burden and Quality of Life in Paroxysmal Atrial Fibrillation; NCT00798356)
This study was approved by the Human Subjects Committee at the University of Kansas Medical Center, approval #11067. The study was supported in part by funds from the KU endowment. All authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- Received February 13, 2012.
- Revision received November 20, 2012.
- Accepted November 22, 2012.
- American College of Cardiology Foundation