Author + information
- Spyridon Deftereos, MD and
- Georgios Giannopoulos, MD∗ ()
- ↵∗Cardiology Department, Athens General Hospital “G. Gennimatas”, 154 Mesogeion Avenue, Athens 11527, Greece
We thank Dr. Zhou and colleagues their interest in our paper (1). However, we would like to note that their arguments pertain to remote ischemic pre-/post-conditioning with the heart as the target organ (all their references are in regard to ischemic conditioning for cardioprotection, not renoprotection). As a result, we cannot really see how their rationale (e.g., regarding times of cardiac ischemia in relation to the conditioning procedure) is of relevance to our study. In any case, we do have the data on times elapsed from the onset of ischemia to the coronary intervention and conditioning procedure. There was no significant difference between the 2 study arms: The median ischemia time was 10 h (interquartile range: 8 to 12 h) in the remote conditioning group versus 9 h (interquartile range: 7 to 13 h) in controls (p = 0.294; Mann-Whitney test).
- American College of Cardiology Foundation