Author + information
- Received February 24, 2013
- Accepted March 20, 2013
- Published online September 24, 2013.
- Surender Deora, MD, DM∗,
- Sunil Gurmukhani, MD∗,
- Sanjay Shah, MD, DM∗,
- Tejas Patel, DM∗,
- Vinod Aggarwal, MS, MCh† and
- Manoj Shah, MD‡
- ∗Department of Cardiology, Sheth V.S. General Hospital, Smt. N.H.L. Municipal Medical College, Gujarat University, Ahmedabad, Gujarat, India
- †Department of Cardiovascular Surgery, Sheth V.S. General Hospital, Smt. N.H.L. Municipal Medical College, Gujarat University, Ahmedabad, Gujarat, India
- ‡Department of Pathology, Gujarat Cancer and Research Institute, Civil Hospital Campus, Gujarat University, Ahmedabad, Gujarat, India
A 26-year-old man presented with gradually progressive dyspnea for the last 1 year. Chest x-ray revealed cardiomegaly (A). Echocardiography showed a dumbbell-shaped mass in the left atrium intermittently obstructing the mitral valve orifice, and a large pericardial mass with massive pericardial effusion (B, arrow, Online Videos 1 and 2). Cardiac magnetic resonance imaging revealed a large, multilobulated soft-tissue mass (85 × 67 mm in the axial plane and 36 × 56 mm in the sagittal plane) involving the left atrial cavity and extending between the aorta (anterior) and the left atrium (posterior) to the pericardial cavity (C, arrow, Online Video 3). During surgery, both the masses were resected (D). Histopathology showed neoplastic spindle and epithelioid cells with mitosis in a myxoid background (hematoxylin and eosin stain, 400×), which on immunohistochemistry was positive for actin and desmin staining, confirming the diagnosis as epithelioid leiomyosarcoma (E). The patient was hemodynamically stable at 1-month follow-up. Ao = aorta; LA = left atrium; LV = left ventricle; R = right; RA = right atrium; RV = right ventricle; V = ventral.
- Received February 24, 2013.
- Accepted March 20, 2013.
- American College of Cardiology Foundation