Author + information
- Yasemin Kaya1,
- Havva Keskin2,
- Kamuran Kalkan3,
- Selim Topçu3,
- İbrahim Halil Tanboğa3,
- Ahmet Kaya4 and
- Enbiya Aksakal3
The association between subclinic hypothyroidism (SH) and cardiac functions has been identified in recent studies. In this study we aimed to examine the cardiac functions with 2D speckle tracking echocardiography (STE) in patient who had SH.
Twenty-five patients (21 women and 4 men) with newly diagnosed SH compared with 23 age- and sex-matched healthy subjects (19 women, 4 men) were evaluated by STE. The diagnosis of SH was based on increased serum thyroid stimulating hormone (TSH) level in the presence of normal free T3 and free T4 levels. For all patients, we evaluated cardiac mechanic functions with STE.
The SH group consisted of 25 patients whose mean age 39±9.4 years and in control group there was 23 healthy subjects whose mean age 38±7.9 years. There was no difference between groups in regarding mitral inflow E, A wave and E/A ratio, whereas mitral deceleration time was shorter in the SH group (p=0.03). Besides, SH patients had shorter E` wave velocity (p:0,02) and higher E/E`ratio (p=0.01). When compared to the control group, left ventricle longitudinal strain values (left ventricle-global strain, left ventricle 4 chamber and left ventricle 2 chamber) were lower in the SH patients (for left ventricle-global strain 17.3+2.2 vs 19.1+2.1, p=0.002). But there was no differences apical rotation, basal rotation and twist between two group.
Our data suggest that SH is associated with impaired left ventricular longitudinal mechanics but not with rotational mechanics.