Author + information
- Ahmet Kaya1,
- Eftal Bakırcı2,
- Zeki Yüksel Günaydın1,
- Ali Bekir Kurt3,
- Kamuran Kalkan4,
- Selim Topçu4 and
- İbrahim Halil Tanboğa4
An increased cardiovascular risk has been evidenced in patients with deep venous thrombosis. We aimed to investigate the relationship between the extent of venous thromboembolism (VTE) and epicardial fat thickness (EFT) and carotid intima-media thickness (CIMT).
In this study 38 patients with VTE (distal and proximal), and 37 age and sex matched patients were enrolled as control group. The patients who had known coronary artery diseases, had abnormal wall motion, and had history of angina were excluded. Echocardiographic EFT and ultrasonographic CIMT were measured in all subjects.
The study group consisted of 38 patients,with a mean age 59±11,(55% male) and 37 healty control group with a mean age 57±12 (54% male). There was no difference between in diabetes mellitus. hypertension, smoking in two groups. Similarly, total cholesterol, low density cholesterol high density cholesterol, and triglicerides levels did not have any difference. According to control group EFT was significantly higher than VTE group (7.1±2.1 mm vs 5.3±2.5 mm, p=0.001). Besides this according to control group CIMT was significantly higher than VTE group. (0.91±0.34 cm vs 0.66±0.22 cm, p<0.001).
This study showed that surrogate markers of atherosclerosis were more frequently seen in patients with VTE. The measurement of EFT and CIMT, may represent a useful and reliable method to evaluate cardiovascular risk in patients with VTE.