Author + information
- Cansın Tulunay Kaya,
- Siamak Mousavi,
- Başar Candemir,
- Ali Timuçin Altın,
- Aydan Ongun,
- Mustafa Kılıçkap,
- Ömer Akyürek,
- Muharrem Güldal,
- Celal Kervancıoğlu and
- Çetin Erol
Atrial fibrillation (AF) is associated with left ventricular diastolic dysfunction. Radiofrequency ablation has been shown to improve left ventricular diastolic functions on short and long term. The data on efficacy of cryoablation on improving diastolic left ventricle functions is less established.
24 consecutive patients (age 22-76 years) undergoing cryoablation for nonvalvular paroxysmal atrial fibrillation were included in the study. Transthoracic echocardiography with mitral inflow pulsed wave Doppler and Pulsed Wave Tissue Doppler Imaging (PWTDI) from mitral medial and lateral annuli was performed before cryoablation for baseline left ventricular diastolic function measurements. The measurements were repeated after two months.
Two patients presenting with AF on the day of the control echocardiogram were excluded. Of the remaining patients preablation and postablation mitral inflow early (E) and late (A) velocities as well as deceleration times were similar. PWTDI of the medial and lateral mitral annulus showed no significant changes in early (E’), late (A’) or systolic (S) velocities after cryoablation. E/E' ratios were calculated in order to estimate left ventricular filling pressures. The values were similar before and after ablation.
Cryoablation of non valvular paroxysmal atrial fibrillation does not influence tissue Doppler derived left ventricular diastolic parameters in short term. Longer term data is warranted as the beneficial effect may be slower before making a conclusion
|Mitral E (cm/s)||77±16||70±13||0.12|
|S med (cm/s)||6.95±1.33||7.21±1.80||0.54|
|S lat (cm/s)||7.60±1.56||8.51±2.96||0.27|
med. medial, lat. lateral