Author + information
- Mustafa Yurtdaş1,
- Yüksel Kaya2,
- Nesim Aladağ3,
- Mahmut Özdemir4,
- Can Baba Arin1,
- Mustafa Tuncer5 and
- Bahattin Balci2
Heart rate recovery (HRR) is influenced by autonomic function. Percutaneous coronary intervention (PCI) improves cardiac symptoms and reduces morbidity and mortality in coronary artery disease (CAD). We aimed to investigate the effect of PCI on HRR and the relationship of HRR index with the degree of coronary stenosis in patients with severe stable CAD.
The treatment group (TG) consisted of 70 severe stable CAD patients treated with PCI, and the control group (CG) with 62 minimal CAD patients, who were not treated with PCI. All participants underwent exercise test both at baseline and 3 months after coronary angiography (CAG)/PCI. HRR was defined as a change in HR from peak exercise to 1 minute after exercise. HRR index was described as the percentage change in HRR from 3 months after CAG/PCI to baseline.
HRR was lower in the TG at baseline (p<0.05), and showed a significant increase after 3 months, when compared with baseline data (p<0.001). In the TG, while HRR was inversely correlated with the number of diseased coronary artery at baseline (r=-0.418, p<0.001), this correlation was not observed after 3 months (p=0.602). HRR index was higher in the TG than the CG (p<0.001). No associations were found between HRR (p=0.136), HRR index (p=0.703) and the severity of coronary stenosis. Patients who had multiple vessels treated, had the highest HRR index.
Our results showed that PCI is associated with improved HRR in proportion to the number of coronary vessels treated in severe stable CAD. In addition to standard exercise test data, the use of HRR may be beneficial for the risk stratification and follow-up of those patients.