Author + information
- Fahriye Vatansever Ağca,
- Kemal Karaagac,
- Tezcan Peker,
- Ozlem Arıcan Ozluk,
- Erhan Tenekecioğu,
- Muhammed Şenturk and
- Mustafa Yılmaz
Coronary artery disease is one of the states which compromise aortic elastic properties. Aortic distensibility is the measurement of aortic elasticity and when the aorta loses its elasticity, aortic expandibility decreases and aortic function is compromised. Aortic stiffness is an independent predictor of cardiovascular risk and mortality. In extend involvement of coronaries, coronary artery by-pass surgery (CABG) is the main choice of treatment. We aimed to investigate the effect of on-pump surgery on aortic functions.
Thirty two (mean age 61,6±9,4 years) consecutive patients with coronary artery disease who underwent on-pump CABG by the same surgeon team were studied. The severity of the disease was evaluated by the Gensini score index. Aortic function indices such as aortic cross-sectional compliance, aortic distensibility and aortic stiffness index were calculated with the use of M-mode echocardiography in preoperative period and at third month postoperatively.
Our study revealed a trend to improvement in aortic functions at post-op three months in patients with severe and extend coronary artery disease with high Gensini score (mean: 98,3 ± 38,1). Exhibiting an increase in aortic cross-sectional compliance from 2,62±1,5 to 3,52±1,6 cm2/mmHg (p=0,20), aortic distensibility from 3,5±2,3 to 4,6± 2,5 cm2/dyne (p=0,29) and a decrease in aortic stiffness index from 3,2±0,7 to 2,9±0,6 (p=0,19). But improvement in aortic functions was not statistically significant.
To the best our knowledge, this is the first study investigating the effect of CABG on aortic functions with multi-vessel coronary artery disease. Our study showed that revascularization via on-pump CABG surgery with aortic cross-clamp doesn't deteriorate aortic functions.