Author + information
- Ahmet Çağrı Aykan1,
- Mustafa Yıldız2,
- Süleyman Karakoyun2,
- Tayyar Gökdeniz1,
- Can Yücel Karabay2,
- İbrahim Akın3 and
- Çetin Gül4
Atherosclerotic renal artery stenosis (ARAS) is associated with uncontrolled hypertension and chronic renal failure. The aim of this study is to evaluate the influence of gender and presence of chronic renal failure on the outcomes of percutaneous transluminal renal artery stenting (PTRAS) due atherosclerosis.
A total of 28 ARAS patients underwent PTRAS and 36 stents were placed. Basal characteristics, laboratory data and blood pressure of patients were recorded. The differences between genders and improvement/deterioration of renal functions and blood pressure were analyzed. The predictors of outcomes were determined.
Baseline characteristics were similar between men and women. Significant improvement of systolic and diastolic blood pressure control was achieved after PTRAS (153.04±17.07 mmHg vs. 124.75±11.40 mmHg, p=0.001 and 92.50±10.76 mmHg vs. 77.54±8.23 mmHg, p<0.001, respectively) (Table-1). Although mean estimated glomerular filtration rate (eGFR) and creatinine levels did not significantly improved at 6 month follow up visit in compared to baseline values, of the 28 patients 13 (46.4%) patients had improvement of renal functions.
Our results suggests that PTRAS is a safe procedure and may offer blood pressure control but beneficial effects of PTRAS on renal function may be anticipated in selected group of patients, especially those with a low eGFR.
|Number of drug||3.71±0.85||2.46±0.69||<0.001|
Table 2: Pre-Percutaneous transluminal renal angioplasty with stent (PTRAS) and at 6 month follow up results of blood pressure, medications, creatinine and estimated glomerular filtration rate. Abbrevations: PTRAS, percutaneous transluminal renal artery stenting; SP, systolic blood pressure; DP, diastolic blood pressure; eGFR, estimated glomerular filtration rate.