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In this study we intended to detect the epidemiological, clinical characteristics and predisposing factors of Infective Endocarditis.
In this retrospective case study of infective endocarditis (IE), the data of patients hospitalized for definite IE in our cardiology clinic were analysed. A total of 194 patients (128 males, 66 females; mean age 48±18 years) admitted with the modified Duke criteria for definitive IE were included in the study within a period of twelve-years between September 2000 and September 2012.
Infective endocarditis developed on a native valve in 169 (87.1%), a mechanical prosthetic valve in 25 (12.9%). Mitral valve was infected in 82 patients (42.2%), aortic valve in 67 patients (34.6%), tricuspidal/pulmonary valve in 15 patients (7.7%) and multiple valves in 30 patients (15.5%) of cases both native and prosthetic valves. Fever was the most common symptom (n=169, 87.1%), while murmur was the most common physical examination finding (n=171, 88.1%). Rheumatic valve disease was the most important predisposing factor (n=43, 22.2%). In 80 patients (41.2%) no predisposing condition was detected. Other common predisposing conditions were having metal prostetic valve (n=24, 12.4%), renal failure (n=11, 5.7%) and having a permanent pacemaker (n=6, 3.1%). The most predisposing circumstances were dental procedures (n=16, 8.2%) and having an hemodialysis catheter (n=11, 5.7%). No predisposing factors were found in %63.9 (n=124) of cases.
That study stated the predisposing factors and circumstances, as far as epidemiological and clinical characteristics of Infective Endocarditis in tertiary center in Turkiye. According to our study the most common predisposing factor was having rheumatic valve disease while the most common predisposing circumstance was having dental procedures.