Author + information
- Salaheddin Akçay1,
- Yasin Turker2,
- Mehmet Ali Kobat3,
- Nurullah Çetin1,
- Ali Riza Bilge1 and
- Ugur Kemal Tezcan1
Hypertension had been reported to affect both the left and the right ventricular functions but its effect on coronary sinus had never been investigated. The aim of this study was to investigate the effect of systemic hypertension on cardiac venous system by evaluating the coronary sinus strain (CSS).
One-hundred-and-twelve hypertensive patients without diabetes and forty-four healthy subjects (the control group) were evaluated consecutively at the outpatient clinic and enrolled in the study. Coronary sinus strain was evaluated with echocardiography in all subjects prior to blood pressure evaluation. 24-hour ambulatory blood pressure monitoring enabled the study population to be divided into 2 groups: 52 patients with dipper pattern hypertension and 60 with non-dipper hypertension.
There was no significant difference regarding demographic characteristics and body mass index between the groups. Non-dipper pattern patients had a lower coronary sinus strain values compared to dippers but the difference did not reach statistical significance (140.8±54.2 and 164±68.4 p=0.087). Non-dipper pattern patients had significantly lower values of CSS compared to control group subjects (140.8±54.2 and 193.9±48.1 p<0.001). Similarly dipper pattern patients had significantly lower values of CSS values compared to controls (164±68.4 and 193.9±48.1 p=0,036). Comparing the three groups, the CSS values showed a progressive decrease from normal people to dipper and non-dipper patients hypertension. Correlation analysis revealed a positive correlation between the aortic strain and the CSS (r:0,247, p=0,002). There was a weak correlation between left ventricular mass and CSS but no correlation was observed between BMI adjusted LV mass and CSS (r:-164 p:0.041 and r=-109 p:0.174).
Our study suggest that systemic hypertension may affect cardiac venous system as well as arterial system that had been reported in many papers. The effect on venous system may be more pronounced in non-dipper pattern hypertension.