Author + information
Wessler JD, Grip LT, Mendell J, Giugliano RP. The P-Glycoprotein Transport System and Cardiovascular Drugs. J Am Coll Cardiol 2013;61:2495–502
The full prescribing information for apixaban (Eliquis) on page 2499 needs to be clarified: “dose reduction for apixaban applies to coadministration of apixaban and strong dual inhibitors of both P-gp and CYP3A4.” This corrects the previous statement that recommends dose reduction of apixaban “when administered with strong P-gp inhibitors.”
The authors apologize for this error.
- American College of Cardiology Foundation