Author + information
- Mark A. Hlatky, MD∗ (, )
- Charlotte Andersson, MD, PhD,
- Tara I. Chang, MD, MS,
- Dhruv Kazi, MD, MS,
- Matthew D. Solomon, MD, PhD and
- Alan S. Go, MD
- ↵∗Department of Health Research and Policy, Stanford University, HRP Redwood Building, Room 150, Stanford, California 94305
We thank Dr. Delgado-Almeida for his interest in our paper (1).
We agree that control of angina and improvement of quality of life are important goals of treatment, but we do not have data on the effect of beta-blocker treatment on these patient-related outcomes. It is important to note that treatments may relieve angina symptoms with no effect on mortality (and vice versa) and that relief of angina remains an important indication for treatment.
Dr. Delgado-Aleida’s comments about the role of the capillary bed, oxygen binding, red blood cell deformation, and vasodilation are interesting and deserve to be investigated. Irrespective of possible mechanisms of action, we need reliable empirical evidence about actual clinical outcomes to inform treatment decisions.
Please note: Philippe Gabriel Steg, MD, served as the Guest Editor for this Letter.
- American College of Cardiology Foundation