|∗10-Year NNT (30% RRR)||∗10-Year NNT (30% RRR)|
|CAC = 0||978||64||139|
|Any CAC present||1,399||28||43|
|CAC = 0||338||223||556|
|Any CAC present||251||46||69|
|Statin not recommended||1,792|
|CAC = 0||1,417||257||371|
|Any CAC present||375||124||159|
NNT = number needed to treat; RRR = relative risk reduction; other abbreviations as in Tables 1 and 2.
↵∗ 30% relative risk reduction from a Cochrane meta-analysis of statin therapy in primary prevention. Statin recommended: patients aged 45 to 75 years of age with primary elevations of LDL–C ≥190 mg/dl, diabetes with LDL-C 70-189 mg/dl, nondiabetic with LDL-C 70-189 mg/dl, and an estimated 10-year ASCVD risk of 7.5% or higher. Statin considered: 10-year ASCVD risk 5% to <7.5%. Statin not recommended: 10-year ASCVD <5%.