|In the absence of a family history of Marfan syndrome, any of the following:|
|In the presence of a family history of Marfan syndrome, any of the following:|
Modified with permission from Loeys et al. (2) Copyright © 2010, British Medical Journal Publishing Group.
↵∗ Caveat: Without discriminating features of another connective tissue disorder such as Loeys-Dietz syndrome, vascular Ehlers-Danlos syndrome, or Shprintzen-Goldberg syndrome, and after mutation analysis for TGFBR1, TGFBR2, TGFB2, SMAD3, SKI, COL3A1, or other genes as appropriate. Other genes/conditions will emerge with time.