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Sleep is an important component of a healthy life. We recently published a meta-analysis, in which a J-shaped relationship was identified between naptime and cardiovascular diseases (Sleep 2015, in press). The relative risk initially decreased from 0 to 30 min/day and then it increased. In this research, we also performed a meta-analysis to investigate the association between daytime sleepiness or napping and the risk of metabolic diseases.
We searched electronic databases for articles published up to October 2015. Dose-response relations were also evaluated by using restricted cubic spline models.
307,237 Asian and Western subjects stratified into 21 categories (reports) were selected. Pooled analysis revealed that excessive daytime sleepiness and a longer nap (>60 min/day) each significantly increased the risk of type 2 diabetes by about 50% compared with the absence of these factors. In contrast, a shorter nap (<60 min/day) did not increase the risk of diabetes (p=0.07). Nap time was not associated with an increased risk of obesity. A dose-response meta-analysis using the cubic spline model showed a J-shaped relationship between nap time and the risk of diabetes or metabolic syndrome, with no effect of napping up to about 40 minutes/day followed by a sharp increase in the risk at longer times (Figure).
Nap time and diabetes or metabolic syndrome may be associated via a J-curve relation. Further studies are needed to confirm the efficacy of a short nap.
Poster Area, South Hall A1
Sunday, April 03, 2016, 9:45 a.m.-10:30 a.m.
Session Title: Contemporary Issues in Preventive Cardiology II
Abstract Category: 33. Prevention: Clinical
Presentation Number: 1191-377
- 2016 American College of Cardiology Foundation