Author + information
- Manuel Sánchez-de-la-Torre, PhD and
- Ferran Barbé, MD∗ ()
- ↵∗Respiratory Department, IRB Lleida. CIBERES, Hospital Universitari Arnau de Vilanova Rovira Roure, 80, 25198 Lleida, Spain
We appreciate Dr. Conti’s comments regarding our study (1) and share his thoughts. However, precision medicine is defined as “treatments targeted to the needs of individual patients on the basis of genetic, biomarker, phenotypic, or psychosocial characteristics that distinguish a given patient from other patients with similar clinical presentations” (2). The HIPARCO score (1,3), based on epigenetics analysis, is able to distinguish “a given patient from other patients with similar clinical presentations.” The results of our study show that if a patient obtains a HIPARCO score of 0 or 6, the probability of making the appropriate clinical decision is higher than 94%. This instrument could help physicians make precise and accurate decisions.
Medicine was originally an art, and the generation of knowledge over time made it a science. Medical practice must become as precise and accurate as possible, and it is the primary role of research to lead the way toward this milestone.
Please note: Both authors have reported that they have no relationships relevant to the contents of this paper to disclose.
- American College of Cardiology Foundation