Author + information
- Yang Shengwen,
- Jiarui Mi,
- Shangyu Liu and
- Zhimin Liu
To evaluate whether the EAARN score can be used to risk-stratify heart failure (HF) patients who underwent Cardiac resynchronization therapy (CRT) and to predict their prognosis.
In this single-center retrospective cohort study, a total of 264 patients which had CRT implantation between January 2010 and December 2014 with heart failure (HF) were enrolled. Primary outcomes were defined as all-cause mortality. Patients were divided into three groups according to EAARN score system: 0-1 scores group (n=199), 2-3 scores group (n=42) and >3 scores group (n=23). Kaplan-Meier analyses for each group and score were analyzed respectively. Discrimination and calibration of EAARN score system were evaluated through c-statistics and Hosmer-Lemeshow(H-L) goodness-of-fit test.
At median 23 months follow-up, 33 patients died, 22 of 199 patients died in 0-1 score group, 5 of 42 died in 2-3 scores group, and 6 of 23 died in >3 scores group. There are no significantly difference among 3 groups (log-rank test, P=0.316). Discrimination of EAARN was inadequate for the outcome(AUC=0.559). EAARN was a good fit of dead for all-cause mortality(P=0.49).
The EAARN score system unsuccessfully stratifies HF patients with CRT.