Author + information
- Wenhui Zhang,
- Xianhui Zhou and
- Baopeng Tang
To assess the safety of cryoablation in atrial fibrillation with systemic review.
We searched Pub Med, CENTRAL in The Cochrane Library, Embase, CBM-Disk, CNKI for published trials, ClinicalTrials.gov, ISI Proceedings for conference abstracts, and WHO International Clinical Trial registration Platform for ongoing studies. The search results were extracted, and then the quality of included studies was assessed. We conducted Meta analysis with STAT 12.
Twenty five clinical trials involving 5214 participants were included. The current data suggest that overall complication incidence was 11.1%, and the most common one was phrenic nerve palsy. Fatal complications were very rare.
Security of cryoablation for atrial fibrillation has been confirmed. Phrenic nerve palsy should be brought to the forefront, although most are reversible. Be prudent about cryoballoon size (larger) may reduce the risk.