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To study the morphologic properties of carotid artery changing regularly with age, and to discuss its aging process in kidney transplant recipients (KTR). cular altered.
Thirty-one patients with end-stage renal disease (ESRD) supported by hemodialysis, 31 KTR and 84 control subjects were offered an ultrasound of carotid artery. The carotid intima-media thickness (CIMT) and diameter (CCAD) of right carotid arteries were measured by ultrasonic frequency tracking. The tends for slope of CIMT vs. age and CCAD vs. age were analyzed by linear regression analysis.
① Compared with KTR group and control group, ESRD group had significantly thicker CIMT and wider CCAD, but there was no significant difference between KTR group and control group. ② The linear regression showed the development of CIMT were positively associated with age (P<0.05). Compared with KTR group and ESRD group respectively, the slope of CIMT vs. age (unstandardized coefficients b) in control group was greater (Z=1.417, P=0.006 and Z=2.223, P<0.001, respectively). There was no significant difference between KTR group and ESRD group (Z=1.038, P=0.723). ③ The development of CCAD were also positively associated with age (P<0.05). Compared with control group, the slope of CCAD vs. age in ESRD group was less (Z=1.677, P=0.002).
After successful kidney transplantation, some morphologic properties of carotid artery are improved and resumes the normal aging process.