Author + information
- Mu Yuming and
- Li Yanhong
The aim of this study was to assess the value of three-dimensional (3D) speckle tracking echocardiography(STE) in the detection of severe multi-vessel coronary stenosis at the resting state.
A total of 101 consecutive patients underwent coronary angiography (CAG), two-dimensional (2D) and 3D echocardiography and 3D-STE on the same day. Left ventricular (LV) global longitudinal strain (GLS), global circumferential strain (GCS), global area strain (GAS), and global radial strain (GRS) were quantified by 3D-STE. ROC were computed to determine optimal strain cutoff values to detect severe multi-vessel coronary stenosis at the resting state.
① 92 of 101 patients were enrolled and divided into the following three groups by the CAG: severe multi-vessel coronary stenosis group (n=38), severe single-vessel coronary stenosis group (n=17) and controls (n=37). ② GLS, GCS, GAS and GRS were significantly decreased in the severe multi-vessel and single-vessel stenosis group compared with the control group; These parameters of the severe multi-vessel coronary stenosis group were more dramatically decreased. Similar changes were also observed for all four 3D-STE parameters in the severe multi-vessel stenosis group than the severe single-vessel coronary stenosis group, whereas only GLS and GAS had statistically significantly decreased (p<0.05). ③ An optimal GLS cutoff value of magnitude ≤-11% with 84.2% sensitivity and GAS cutoff value of magnitude ≤-20% with 80% specificity detected severe multi-vessel coronary stenosis.
Global strain by 3D-STE is useful to detect severe multi-vessel coronary stenosis, wherein GLS and GAS are more valuable indicators.