Author + information
- Zhang Hui,
- Yangling Zhang,
- Yongjiang Mao,
- Guanghui Guo and
- Rongqin Zheng
Use echocardiography to study gender differences of relevant parameters of non-physiologic tricuspid regurgitation in healthy old people.
Study subjects included 873 healthy people (392 men, mean age 59±6 years, 481 women, mean age 56±8 years) examed in the Third Affiliated Hospital of Sun Yat-sen University from May 2014 to May 2015. They were all nonsmokers. All subjects had no history of heart diseases, normal blood tests and normal resting 12-lead ECGs. We used an ultrasound apparatus (A10 and F75, Hitachi-Aloka Company, Tokyo, Japan) with a UST-52105 cardiac probe (Hitachi-Aloka). Before examination, every person had a rest for 10 minutes. After a conventional echocardiographic examination, the largest area view of tricuspid regurgitation was selected. Color doppler sampling volume includes all right atrium, tricuspid valve and part of the right ventricle. The area of tricuspid regurgitation was measured, and regurgitation area >1.5 cm2 was defined as the non-physiologic regurgitation. Use continuous-wave Doppler to measure maximum pressure gradient of tricuspid regurgitation. Data were processed using commercial software (SPSS 19.0, IBM, Armonk NY, USA). Numerical data are presented as mean standard deviation (SD). Differences between two groups of men and women using t test, with a P<0.05 considered statistically.
Compared male group with female group, the incidence of non-physiologic tricuspid regurgitation was higher in female group (34±13% vs 16±7%, P<0.05). The non-physiologic tricuspid regurgitation area was larger in female group (2.71±1.04 cm2 vs 4.22±1.64 cm2, P<0.05). But the pressure gradient of the tricuspid regurgitation has no statistical differences in two groups (27±11 mmHg vs 24±10 mmHg, P>0.05).
Gender may influence incidence and flow area of non-physiologic tricuspid regurgitation in healthy old people.