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To examine endpoints in patients with chronic heart failure ilure (CHF) after myocardial infarction.
225 male patients at the age of 40 to 60 years old with CHF have been examined. All patients were divided into three groups by functional class (FC) CHF: 40 patients with CHF I FC, 88 patients with CHF II FC and 97 patients with CHF III FC. We examined the main predictors of poor prognosis in patients with chronic heart failure during long-term follow-up - three years.
The analysis endpoints showed that in 3 years of follow-noted development reinfarction in 43 (19.1%) cases, including 15 fatal and nonfatal 28, and 18 cases of sudden death. Analysis of prognostic parameters showed that patients who developed adverse outcomes for extended surveillance had a high FC CHF, greater number of heart rate (HR), lower left ventricular ejection fraction (LVEF) less than 40%, as well as high levels of noradrenalin compared with patients who not have the MTR. Lethality has strong positive correlation with high and average-high meanings of noradrenaline (r=0,78, r=0,70; P<0,01accordingly).
Determination of early predictors of poor prognosis in patients with CHF identifies patients at high cardiovascular risk and poor prognosis and undertake prevention of complications, optimization of treatment.