Author + information
- Zhou Ling and
- Minjuan Zheng
To investigate the epidemiological characteristics, clinical manifestations, treatment and prognosis of acute aortic dissection and improve the diagnostic and interventional approaches.
We collected clinical data from 1220 cases of acute aortic dissections (from 2007 to 2015, Xi'an, Shaanxi Province) and analyzed the epidemiological characteristics, high-risk factors, major organ complications, surgical intervention and prognosis.
1. Epidemiological characteristics: The average age of patients suffering from acute aortic dissection is 49.75 years old. Among them, the patients with Marfan's syndrome have an average age of 34.04 years old. The male-to-female ratio is 3.38. 2. First presenting symptoms: 970 patients (79.50%) presented with chest pain and 30 patients (2.45%) presented with abdominal pain. 3. History and involved organs: 971 patients have a history of high blood pressure. The numbers of dissections that involve cervical, abdominal arteries are 295 and 318 respectively. 430 patients presented with vascular involvement and simultaneous thrombosis. 947 patients received surgery and the mortality rate is 14.01%, with 89 presurgical and 82 postsurgical deaths. The causes of death are mostly multi-organ dysfunction, heart failure, cardiac arrhythmia and neurological complications.
Acute aortic dissection is a high-risk disease with high mortality rate (most of the Stanford A) which requires early interventional treatment.