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More than 2.5 million people die of myocardial infarction each year in the world, 25% of them caused by acute myocardial infarction (AMI). The early diagnosis of AMI in the “Golden Period” plays a crucial role in saving the patient's life. Evaluate the value of Troponin I, a cardiac marker with high sensitivity and specificity for AMI is very necessary.
To identify the value of hs-Troponin I in early diagnosis of AMI.
Using cross-sectional study, the research is carried out on 60 patients admitted to hospital, presented with chest pain or chest discomfort in the first 12 hours from May 2015 to March 2016. The patients were withdrawn 2 ml of blood to determine hs-Troponin I levels by Architect i-2000 system. The diagnosis bases on coronary CT angiography in 128-slice CT scanner and ECG.
The final results showed that AMI was diagnosed in 33 out of 60 cases, which account for 55%. Hs-Troponin I levels of patients in AMI groups were considerably higher than those with other diagnoses. Area under the ROC curve in AMI diagnosis of hs-Troponin I was 0.957. Sensitivity, specificity, positive and negative predictive value of hs-Troponin I at the level of 41.55 ng/L were 91.0%, 89.0%, 91.0% and 89.0%, respectively.
The value of high sensitive Troponin-I holds the key position in early diagnosis of AMI.