Author + information
- Li Yong,
- Baoxin Liu,
- Qiqiang Jie and
- Yidong Wei
The aims of this study were to find out the potential relationship between protein Z plasma levels and myocardial infarction and the impact of PCI and stent implantation on plasma protein Z concentration.
We studied protein Z levels in 85 patients (48 male, 37 female) admitted to Shanghai Tenth People's Hospital with a clinical manifestation of myocardial infarction (MI), and in 15 healthy subjects selected to be comparable to the patients group in terms of age and gender.
PZ levels of myocardial infarction patients were significantly lower compared to controls (1586.7±717.6 ng/mL vs. 2518.0±971.1 ng/mL P0.01) whereas the protein Z plasma levels of MI patients before and after percutaneous coronary intervention (PCI) were not significantly changed.
The results of our study suggest that myocardial infarction is related to low protein Z levels and that thrombosis is associated with low PZ concentrations.