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Many epidemiological studies highlight the so-called risk factors (RF), the presence of which increases the likelihood of developing cardiovascular disease and worsens its forecast. In the development of coronary heart disease (CHD) in women, in addition to traditional RF (arterial hypertension (AH), obesity, lipid disorders, diabetes) is isolated and specific RF, such as menopause, use of oral contraceptives etc.
To conduct a comparative analysis of the occurrence of the major risk factors of CHD in women of childbearing age and menopause.
200 women were examined with established CHD, who were selected as a result of the epidemiological and clinical examination. In the reproductive age was 79, and in menopause- 121.
All surveyed conducted ECG study, measured blood pressure (BP), defined abdominal obesity (AO) and determined the anthropometric data with the calculation of the index of Ketlet and studied lipid profile - total cholesterol (TC), triglycerides (TG), and calculated atherogenic index (AI). Low physical activity (LPA) was determined by filling in a special questionnaire.
The obtained data were processed by methods of medical statistics.
The study found that the overall frequency of all studied RF registration with almost equal frequency in women met in both age groups. The most common RF were AO, which amounted to 94.5% in the fertile and 93.2% in menopause age. Then followed overweight (BMI), which in postmenopausal women was greater than that in fertile period- 93.5% and 91.7% respectively. Such an important RF as AH is much more common in women in menopause, compared with patients of fertile age (61.4% and 27.3%). From the lipid profile prevailed gipertriglitsiridemiya (GTG)-81.8% in menopause, against 70.9% in reproductive age), then hypercholesterolemia (GC)-63.0 and 78.2%, respectively), LDL -C-(46.4 and 70.2% respectively), with almost the same frequency occurs AI (49.5 and 67.3%, respectively). LPA also more frequent in postmenopausal women compared with those of fertile age (81.8 and 67.3%, respectively).
1. This study showed that among women with CHD is the most common RF such AO, BMI, GTG, and GC.
2. In both age groups all the RF with the exception of AH occur with equal frequency.
3. In comparison with persons of fertile age AH is more common in postmenopausal women.