Author + information
- Liu Dinghui,
- Jianrui Zheng,
- Shujie Yu,
- Bin Zhou,
- Lin Wu,
- Min Wang and
- Xiaoxian Qian
To investigate the relationship between apolipoprotein (apo) A and the extent of coronary artery lesions in Chinese type 2 diabetics with coronary heart disease.
Totally 184 type 2 diabetic patients diagnosed with coronary heart disease by coronary angiography were enrolled. The level of apoA was measured by ELISA. Gensini score was used to assess the severity of coronary artery lesions by coronary angiography results. Association between Gensini score, branches of coronary artery lesions, diffuse lesions, complete occlusive lesions and apoA were evaluated by Spearman's rank correlation analysis. All statistical tests were operated with the program SPSS 13.0 and P < 0.05 was considered as statistical significance.
With the increase of apoA, Gensini score decreased significantly (r = -0.151, P = 0.043). There were no statistical significances between branches of coronary artery lesions (r = -0.1, P = 0.182), diffuse lesions (r = 0.045, P = 0.569), complete occlusive lesions (r = -0.102, P = 0.173) and apoA.
Among Chinese type 2 diabetics with coronary heart disease, apoA is significantly correlated with the extent of coronary artery lesions.