Author + information
- Li Faquan,
- Yiming Zhong,
- Aiqin Zhou and
- Faquan Li
To observe the correlation of plasma B-type natriuretic peptide, interleukin 6, tumor necrosis factor α and high sensitivity C reactive protein in patients with acute coronary syndrome.
162 patients with acute coronary syndrome were consecutive selected, including ST segment elevation myocardial infarction (STEMI) 98 cases, non-ST segment elevation myocardial infarction (NSTEMI) 39 cases, unstable angina pectoris (UAP) 25 cases and 160 healthly controls. Blood samples were collected from patients and controls, plasma BNP was measured by chemiluminescence immunoassay, the contents of IL-6, TNF-α was determined by ELISA and hs-CRP by immune turbidimetric method. Rule out infectious diseases, cancer, collagen diseases, application of immunosuppressive drugs.
ACS group BNP, IL-6, TNF-α, hs-CRP levels were significantly higher than the control group (P <0.01).
BNP and inflammatory factors IL-6, TNF-α, hs-CRP in ACS patients was significantly higher and BNP was positively correlated. with inflammatory factors IL-6, TNF-α, hs-CRP.