Author + information
- Ngai Yin Chan1,
- Chi Chung Choy1,
- Kang Yin Lee2,
- Leung Kwai Chan2,
- Raymond Fung3,
- Gabriel Yip3,
- Anna Chan4,
- Gary Shing Him Cheung4,
- Simon Lam5 and
- Kin Lam Tsui6
- 1Department of Medicine & Geriatrics Princess Margaret Hospital, Kowloon, Hong Kong
- 2Department of Medicine, Queen Elizabeth Hospital, Kowloon, Hong Kong
- 3Cardiac Medical Unit, Grantham Hospital, Hong Kong, Hong Kong
- 4Department of Medicine & Therapeutics, Prince of Wales Hospital, Hong Kong, Hong Kong
- 5Department of Medicine, Queen Mary Hospital, Hong Kong, Hong Kong
- 6Department of Medicine, Pamela Youde Nethersole Hospital, Chai Wan, Hong Kong, Hong Kong
Percutaneous left atrial appendage occlusion (LAAO) is a recently available interventional procedure for stroke prevention in atrial fibrillation (AF). However, real-world data in Asians, especially Chinese population is limited.
The Hong Kong LAAO Registry was established to collect patient and procedural characteristics, acute procedural outcomes, complications and long-term outcomes of LAAO procedures in the public hospitals in Hong Kong.
One hundred and thirty patients (50 female, mean age 71.8±8.7) with non-valvular AF (50 paroxysmal and 80 non-paroxysmal AF) and contraindications to long-term oral anticoagulation underwent LAAO with Amplatzer Cardiac Plug/Amulet (St Jude Medical, St Paul, MN, USA) (n=60) and Watchman (Boston Scientific Corp, Minneapolis, MN, USA) (n=70). The mean CHA2DS2VASc score was 4.1±1.4 and HAS-BLED score was 2.7±1.3. Acute procedural success was achieved in 128 (98.5%) patients. 30-day major complications occurred in 8 (6.2%) patients with 1 mortality, 1 stroke, 4 cardiac tamponade, 4 major bleeding, 2 cardiovascular surgical repair and 1 device embolization. On 1-year follow-up, one (1.6%) out of 63 patients suffered from stroke. Compared with an expected annualized stroke rate of 3.7%, there was a 58.6% reduction (p=0.288).
The acute procedural success and complication rate of LAAO in a Chinese population were comparable to previous studies in the Western counterparts. A similar magnitude of reduction in annualized stroke rate was also observed.
STRUCTURAL: Left Atrial Appendage Exclusion