Attenuated-Signal Plaque Progression Predicts Long-Term Mortality After Heart Transplantation
IVUS Assessment of Cardiac Allograft Vasculopathy
Kozo Okada, William F. Fearon, Helen Luikart, Hideki Kitahara, Kyuhachi Otagiri, Shigemitsu Tanaka, Takumi Kimura, Paul G. Yock, Peter J. Fitzgerald, Alan C. Yeung, Hannah A. Valantine, Kiran K. Khush and Yasuhiro Honda
This retrospective study aimed to characterize the association between attenuated-signal plaque (ASP) and long-term mortality post-heart transplantation. (A) During the first year post-transplant, patients with ASP progression experienced significantly greater acute cellular rejection. (B) Patients with ASP progression at 1 year also demonstrated a significantly lower long-term event-free survival rate. CI = confidence interval; IVUS = intravascular ultrasound.